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| カタログ番号 | HF975014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ADCY5 Polyclonal Antibody (HF975014) is a rabbit polyclonal antibody detecting ADCY5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ADCY5 (Ser1066-Ser1261). | ||||||||
| ターゲット | AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95622 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Adenylate cyclase type 5 (ADCY5) is a ~138 kDa protein. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. 1. Ding, Q. et al. (2004) Molecular pharmacology 66, 921-8. PMID: 15385642 2. Chen, YZ. et al. (2014) Annals of neurology 75, 542-9. PMID: 24700542 3. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 4. Hodson, DJ. et al. (2014) Diabetes 63, 3009-21. PMID: 24740569 | ||||||||
| 注意事項 | For research use only. |
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