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Anti-ADCY6 Polyclonal Antibody (HT259014)

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Anti-ADCY6 Polyclonal Antibody
Anti-ADCY6 Polyclonal Antibody
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Aperçu
Numéro de catalogueHT259014
Description
Anti-ADCY6 Polyclonal Antibody (HT259014) is a rabbit polyclonal antibody detecting ADCY6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human ADCY6 (Gln373-Gly579).
Cible Adenylate cyclase type 6, KIAA0422, ATP pyrophosphate-lyase 6, ADCY6, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, Adenylate cyclase type VI
Purification Purified by antigen affinity column.
Numéro d'accès O43306
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Adenylate cyclase type 6 (ADCY6) is a ~130 kDa protein. Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors. Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells. Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion.

1. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384
2. Gros, R. et al. (2007) Arteriosclerosis, thrombosis, and vascular biology 27, 2657-63. PMID: 17916776
Note For research use only.
Images
  • Anti-ADCY6 Polyclonal Antibody

    Western blot

    Lane 1: Hela cell lysate
    Lane 2: PC-3 cell lysate

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-ADCY6 Polyclonal Antibody

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