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| カタログ番号 | HT259014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ADCY6 Polyclonal Antibody (HT259014) is a rabbit polyclonal antibody detecting ADCY6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ADCY6 (Gln373-Gly579). | ||||||||
| ターゲット | Adenylate cyclase type 6, KIAA0422, ATP pyrophosphate-lyase 6, ADCY6, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, Adenylate cyclase type VI | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43306 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Adenylate cyclase type 6 (ADCY6) is a ~130 kDa protein. Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors. Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells. Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion. 1. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 2. Gros, R. et al. (2007) Arteriosclerosis, thrombosis, and vascular biology 27, 2657-63. PMID: 17916776 | ||||||||
| 注意事項 | For research use only. |
Lane 1: Hela cell lysate
Lane 2: PC-3 cell lysate
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