

| Каталожный номер | HT259014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-ADCY6 Polyclonal Antibody (HT259014) is a rabbit polyclonal antibody detecting ADCY6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human ADCY6 (Gln373-Gly579). | ||||||||
| Цель | Adenylate cyclase type 6, KIAA0422, ATP pyrophosphate-lyase 6, ADCY6, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, Adenylate cyclase type VI | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O43306 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Adenylate cyclase type 6 (ADCY6) is a ~130 kDa protein. Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors. Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells. Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion. 1. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 2. Gros, R. et al. (2007) Arteriosclerosis, thrombosis, and vascular biology 27, 2657-63. PMID: 17916776 | ||||||||
| Примечание | For research use only. |

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Lane 2: PC-3 cell lysate
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