Anti-ADRM1 Polyclonal Antibody (HS705014)

Name: Anti-ADRM1 Polyclonal Antibody
Brand: abinScience
SKU: HS705014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HS705014

Description

Anti-ADRM1 Polyclonal Antibody (HS705014) is a rabbit polyclonal antibody detecting ADRM1 in ELISA, IHC, WB. Suitable for Bovine, Chicken, Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human ADRM1 (Thr2-Asp407).

Cible

Adhesion-regulating molecule 1, ADRM1, GP110, Rpn13 homolog, 110 kDa cell membrane glycoprotein, hRpn13, Gp110, Proteasome regulatory particle non-ATPase 13, ARM-1, Proteasomal ubiquitin receptor ADRM1

Purification

Purified by antigen affinity column.

Numéro d'accès

Q16186

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Proteasomal ubiquitin receptor ADRM1 is a ~42 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.

1. Jørgensen, JP. et al. (2006) Journal of molecular biology 360, 1043-52. PMID: 16815440

2. Yao, T. et al. (2006) Nature cell biology 8, 994-1002. PMID: 16906146

3. Hamazaki, J. et al. (2006) The EMBO journal 25, 4524-36. PMID: 16990800

4. Qiu, XB. et al. (2006) The EMBO journal 25, 5742-53. PMID: 17139257

5. Husnjak, K. et al. (2008) Nature 453, 481-8. PMID: 18497817

6. Jiao, L. et al. (2014) Protein & cell 5, 616-30. PMID: 24752541

7. Sahtoe, DD. et al. (2015) Molecular cell 57, 887-900. PMID: 25702870

8. Vander Linden, RT. et al. (2015) Molecular cell 57, 901-911. PMID: 25702872

Note

For research use only.

Images

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Fiche technique

Anti-ADRM1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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