Anti-ADRM1 Polyclonal Antibody (HS705014)

Name: Anti-ADRM1 Polyclonal Antibody
Brand: abinScience
SKU: HS705014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HS705014

説明

Anti-ADRM1 Polyclonal Antibody (HS705014) is a rabbit polyclonal antibody detecting ADRM1 in ELISA, IHC, WB. Suitable for Bovine, Chicken, Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human ADRM1 (Thr2-Asp407).

ターゲット

Adhesion-regulating molecule 1, ADRM1, GP110, Rpn13 homolog, 110 kDa cell membrane glycoprotein, hRpn13, Gp110, Proteasome regulatory particle non-ATPase 13, ARM-1, Proteasomal ubiquitin receptor ADRM1

精製

Purified by antigen affinity column.

アクセッション番号

Q16186

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Proteasomal ubiquitin receptor ADRM1 is a ~42 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.

1. Jørgensen, JP. et al. (2006) Journal of molecular biology 360, 1043-52. PMID: 16815440

2. Yao, T. et al. (2006) Nature cell biology 8, 994-1002. PMID: 16906146

3. Hamazaki, J. et al. (2006) The EMBO journal 25, 4524-36. PMID: 16990800

4. Qiu, XB. et al. (2006) The EMBO journal 25, 5742-53. PMID: 17139257

5. Husnjak, K. et al. (2008) Nature 453, 481-8. PMID: 18497817

6. Jiao, L. et al. (2014) Protein & cell 5, 616-30. PMID: 24752541

7. Sahtoe, DD. et al. (2015) Molecular cell 57, 887-900. PMID: 25702870

8. Vander Linden, RT. et al. (2015) Molecular cell 57, 901-911. PMID: 25702872

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-ADRM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-ADRM1 Polyclonal Antibody (HS705014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ