

| Numéro de catalogue | HV632014 | ||||||||
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| Description |
Anti-AKT3 Polyclonal Antibody (HV632014) is a rabbit polyclonal antibody detecting AKT3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AKT3 (Met1-Lys143). | ||||||||
| Cible | PKBG, PKB gamma, AKT3, STK-2, Protein kinase B gamma, RAC-PK-gamma, RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Y243 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | RAC-gamma serine/threonine-protein kinase (AKT3) is a ~55 kDa protein. AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. | ||||||||
| Note | For research use only. |
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