Anti-ALDH7A1 Polyclonal Antibody (HW546014)

Name: Anti-ALDH7A1 Polyclonal Antibody
Brand: abinScience
SKU: HW546014
Price: 96 USD
Availability: InStock

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Número de catálogo

HW546014

Descripción

Anti-ALDH7A1 Polyclonal Antibody (HW546014) is a rabbit polyclonal antibody detecting ALDH7A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).

Objetivo

ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1

Purificación

Purified by antigen affinity column.

Número de acceso

P49419

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.

1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085

2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735

3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659

4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592

5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827

6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938

7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343

8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394

9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-ALDH7A1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: 293T cell lysate
Lane 2: Mouse liver lysate
Lane 3: Rat liver lysate
Lane 4: Rat kidney lysate

Referencias

Datasheet

Anti-ALDH7A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-ALDH7A1 Polyclonal Antibody (HW546014)

Vista general

Imágenes

Referencias

Datasheet

SDS