中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HW546014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ALDH7A1 Polyclonal Antibody (HW546014) is a rabbit polyclonal antibody detecting ALDH7A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539). | ||||||||
| ターゲット | ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P49419 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. 1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085 2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735 3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659 4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592 5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827 6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938 7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343 8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394 9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-ALDH7A1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: 293T cell lysate
Lane 2: Mouse liver lysate
Lane 3: Rat liver lysate
Lane 4: Rat kidney lysate
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
