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Anti-ALDH7A1 Polyclonal Antibody
Anti-ALDH7A1 Polyclonal Antibody
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Обзор
Каталожный номерHW546014
Описание
Anti-ALDH7A1 Polyclonal Antibody (HW546014) is a rabbit polyclonal antibody detecting ALDH7A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).
Цель ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1
Очистка Purified by antigen affinity column.
Номер доступа P49419
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.

1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085
2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735
3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659
4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592
5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827
6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938
7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343
8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394
9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740
Примечание For research use only.
Изображения
  • Anti-ALDH7A1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-ALDH7A1 polyclonal antibody at 1µg/ml on various samples.
    Lane 1: 293T cell lysate
    Lane 2: Mouse liver lysate
    Lane 3: Rat liver lysate
    Lane 4: Rat kidney lysate

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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