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| カタログ番号 | HY281014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-AMBP Polyclonal Antibody (HY281014) is a rabbit polyclonal antibody detecting AMBP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AMBP (Val22-Val203). | ||||||||
| ターゲット | AMBP, HCP, Complex-forming glycoprotein heterogeneous in charge, ITIL, Bikunin, Protein HC, EDC1, HI-30, Uronic-acid-rich protein, Protein AMBP, ITI-LC, Alpha-1 microglycoprotein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P02760 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein AMBP (α-MG) is a ~38 kDa protein. Antioxidant and tissue repair protein with reductase, heme-binding and radical-scavenging activities. Removes and protects against harmful oxidants and repairs macromolecules in intravascular and extravascular spaces and in intracellular compartments. Intravascularly, plays a regulatory role in red cell homeostasis by preventing heme- and reactive oxygen species-induced cell damage. Binds and degrades free heme to protect fetal and adult red blood cells from hemolysis. Reduces extracellular methemoglobin, a Fe3+ (ferric) form of hemoglobin that cannot bind oxygen, back to the Fe2+ (ferrous) form deoxyhemoglobin, which has oxygen-carrying potential. 1. Allhorn, M. et al. (2002) Blood 99, 1894-901. PMID: 11877257 2. Allhorn, M. et al. (2005) Free radical biology & medicine 38, 557-67. PMID: 15683711 3. Olsson, MG. et al. (2011) PloS one 6, e27505. PMID: 22096585 4. Olsson, MG. et al. (2013) Antioxidants & redox signaling 18, 2017-28. PMID: 23157686 5. Rutardottir, S. et al. (2013) Free radical research 47, 541-50. PMID: 23642167 6. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 7. Kristiansson, A. et al. (2021) Free radical biology & medicine 162, 149-159. PMID: 32092412 8. Kristiansson, A. et al. (2020) International journal of molecular sciences 21. PMID: 32823731 | ||||||||
| 注意事項 | For research use only. |
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