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| カタログ番号 | HB958014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-AOC1/DAO Polyclonal Antibody (HB958014) is a rabbit polyclonal antibody detecting AOC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AOC1/DAO (Glu20-Trp322). | ||||||||
| ターゲット | AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P19801 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Diamine oxidase [copper-containing] (AOC1/DAO) is a ~85 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes. 1. Elmore, BO. et al. (2002) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 7, 565-79. PMID: 12072962 2. McGrath, AP. et al. (2009) Biochemistry 48, 9810-22. PMID: 19764817 3. Hölttä, E. et al. (1975) The Biochemical journal 145, 373-8. PMID: 239684 4. Novotny, WF. et al. (1994) The Journal of biological chemistry 269, 9921-5. PMID: 8144586 | ||||||||
| 注意事項 | For research use only. |
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