

| Каталожный номер | HB958014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-AOC1/DAO Polyclonal Antibody (HB958014) is a rabbit polyclonal antibody detecting AOC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human AOC1/DAO (Glu20-Trp322). | ||||||||
| Цель | AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P19801 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Diamine oxidase [copper-containing] (AOC1/DAO) is a ~85 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes. 1. Elmore, BO. et al. (2002) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 7, 565-79. PMID: 12072962 2. McGrath, AP. et al. (2009) Biochemistry 48, 9810-22. PMID: 19764817 3. Hölttä, E. et al. (1975) The Biochemical journal 145, 373-8. PMID: 239684 4. Novotny, WF. et al. (1994) The Journal of biological chemistry 269, 9921-5. PMID: 8144586 | ||||||||
| Примечание | For research use only. |
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