Anti-AP2M1 Polyclonal Antibody (HV707014)

Name: Anti-AP2M1 Polyclonal Antibody
Brand: abinScience
SKU: HV707014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HV707014

Description

Anti-AP2M1 Polyclonal Antibody (HV707014) is a rabbit polyclonal antibody detecting AP2M1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human AP2M1 (Arg170-Cys435).

Cible

Adaptor-related protein complex 2 subunit mu, AP-2 mu chain, CLAPM1, HA2 50 kDa subunit, Plasma membrane adaptor AP-2 50 kDa protein, Adaptin-mu2, AP2M1, KIAA0109, Clathrin coat assembly protein AP50, Adaptor protein complex AP-2 subunit mu, Clathrin assembly protein complex 2 mu medium chain, AP-2 complex subunit mu, Clathrin coat-associated protein AP50

Purification

Purified by antigen affinity column.

Numéro d'accès

Q96CW1

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

AP-2 complex subunit mu (AP2M1) is a ~49 kDa protein. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components.

1. Fraile-Ramos, A. et al. (2003) Traffic (Copenhagen, Denmark) 4, 243-53. PMID: 12694563

2. Motley, A. et al. (2003) The Journal of cell biology 162, 909-18. PMID: 12952941

3. Nakatsu, F. et al. (2003) Cell structure and function 28, 419-29. PMID: 14745134

4. Huang, F. et al. (2004) The Journal of biological chemistry 279, 16657-61. PMID: 14985334

5. Owen, DJ. et al. (2004) Annual review of cell and developmental biology 20, 153-91. PMID: 15473838

6. Helbig, I. et al. (2019) American journal of human genetics 104, 1060-1072. PMID: 31104773

9. Marcello, E. et al. (2013) The Journal of clinical investigation 123, 2523-38. PMID: 23676497

Note

For research use only.

Images

Reférences

Fiche technique

Anti-AP2M1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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