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| カタログ番号 | HT170014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-AP3B1 Polyclonal Antibody (HT170014) is a rabbit polyclonal antibody detecting AP3B1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AP3B1 (Met1-Leu233). | ||||||||
| ターゲット | Clathrin assembly protein complex 3 beta-1 large chain, ADTB3A, Adaptor protein complex AP-3 subunit beta-1, Beta-3A-adaptin, AP3B1, Adaptor-related protein complex 3 subunit beta-1, AP-3 complex subunit beta-1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O00203 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | AP-3 complex subunit beta-1 (AP3B1) is a ~121 kDa protein. Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. | ||||||||
| 注意事項 | For research use only. |
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