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Anti-AP4M1 Polyclonal Antibody (HC009014)

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Aperçu
Numéro de catalogueHC009014
Description
Anti-AP4M1 Polyclonal Antibody (HC009014) is a rabbit polyclonal antibody detecting AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2 in ELISA, IHC, WB. Suitable for Human, Bovine, Dog, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human AP4M1 (Lys184-Ile453).
Cible AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès O00189, Q29RY8, E2RED8, Q2PWT8, Q9JKC7
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

AP-4 complex subunit mu-1 (AP4M1) is a ~49 kDa protein. Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons.

1. Dell'Angelica, EC. et al. (1999) The Journal of biological chemistry 274, 7278-85. PMID: 10066790
2. Hirst, J. et al. (1999) Molecular biology of the cell 10, 2787-802. PMID: 10436028
3. Aguilar, RC. et al. (2001) The Journal of biological chemistry 276, 13145-52. PMID: 11139587
4. Simmen, T. et al. (2002) Nature cell biology 4, 154-9. PMID: 11802162
5. Burgos, PV. et al. (2010) Developmental cell 18, 425-36. PMID: 20230749
Note For research use only
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Formula
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