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Anti-AP4M1 Polyclonal Antibody (HC009014)

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概要
カタログ番号HC009014
説明
Anti-AP4M1 Polyclonal Antibody (HC009014) is a rabbit polyclonal antibody detecting AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2 in ELISA, IHC, WB. Suitable for Human, Bovine, Dog, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant human AP4M1 (Lys184-Ile453).
ターゲット AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2
エンドトキシンレベル Please contact with the lab for this information.
精製 Purified by antigen affinity column.
アクセッション番号 O00189, Q29RY8, E2RED8, Q2PWT8, Q9JKC7
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

AP-4 complex subunit mu-1 (AP4M1) is a ~49 kDa protein. Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons.

1. Dell'Angelica, EC. et al. (1999) The Journal of biological chemistry 274, 7278-85. PMID: 10066790
2. Hirst, J. et al. (1999) Molecular biology of the cell 10, 2787-802. PMID: 10436028
3. Aguilar, RC. et al. (2001) The Journal of biological chemistry 276, 13145-52. PMID: 11139587
4. Simmen, T. et al. (2002) Nature cell biology 4, 154-9. PMID: 11802162
5. Burgos, PV. et al. (2010) Developmental cell 18, 425-36. PMID: 20230749
注意事項 For research use only
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参考文献
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