

| Número de catálogo | HV437014 | ||||||||
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| Descripción |
Anti-API5 Polyclonal Antibody (HV437014) is a rabbit polyclonal antibody detecting API5 in ELISA, IHC, WB. Suitable for Human, Mouse, Chicken, Pongo abelii, and Xenopus laevis.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human API5 (Pro2-Phe360). | ||||||||
| Objetivo | API5, Fibroblast growth factor 2-interacting factor, AAC-11, Apoptosis inhibitor 5, Antiapoptosis clone 11 protein, Protein XAGL, API-5, Cell migration-inducing gene 8 protein, FIF | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9BZZ5 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Apoptosis inhibitor 5 (API5) is a ~59 kDa protein. Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. | ||||||||
| Nota | For research use only. |
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