

| Número de catálogo | HT226014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-AQP9 Polyclonal Antibody (HT226014) is a rabbit polyclonal antibody detecting AQP9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human AQP9 (Tyr125-Leu158). | ||||||||
| Objetivo | AQP-9, SSC1, Small solute channel 1, Aquaporin-9, AQP9, Aquaglyceroporin-9 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O43315 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Aquaporin-9 (AQP9) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. AQP9 is the primary route for glycerol uptake in hepatocytes, supporting hepatic gluconeogenesis. It exhibits broad specificity and may transport various small, non-charged solutes, including carbamides, polyols, purines, and pyrimidines. AQP9 may also facilitate hepatic urea extrusion. Due to its permeability to lactate, AQP9 might participate in the astrocyte-to-neuron lactate shuttle, supplying neurons with energy. 1. Tsukaguchi, H. et al. (1999) The American journal of physiology 277, F685-96. PMID: 10564231 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Geistlinger, K. et al. (2022) Life (Basel, Switzerland) 12. PMID: 35054513 4. Ishibashi, K. et al. (1998) Biochemical and biophysical research communications 244, 268-74. PMID: 9514918 | ||||||||
| Nota | For research use only. |
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