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| カタログ番号 | HT226014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-AQP9 Polyclonal Antibody (HT226014) is a rabbit polyclonal antibody detecting AQP9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AQP9 (Tyr125-Leu158). | ||||||||
| ターゲット | AQP-9, SSC1, Small solute channel 1, Aquaporin-9, AQP9, Aquaglyceroporin-9 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43315 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Aquaporin-9 (AQP9) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. AQP9 is the primary route for glycerol uptake in hepatocytes, supporting hepatic gluconeogenesis. It exhibits broad specificity and may transport various small, non-charged solutes, including carbamides, polyols, purines, and pyrimidines. AQP9 may also facilitate hepatic urea extrusion. Due to its permeability to lactate, AQP9 might participate in the astrocyte-to-neuron lactate shuttle, supplying neurons with energy. 1. Tsukaguchi, H. et al. (1999) The American journal of physiology 277, F685-96. PMID: 10564231 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Geistlinger, K. et al. (2022) Life (Basel, Switzerland) 12. PMID: 35054513 4. Ishibashi, K. et al. (1998) Biochemical and biophysical research communications 244, 268-74. PMID: 9514918 | ||||||||
| 注意事項 | For research use only. |
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