Anti-AR Polyclonal Antibody (HY315014)

Name: Anti-AR Polyclonal Antibody
Brand: abinScience
SKU: HY315014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
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Número:

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY315014

Descripción

Anti-AR Polyclonal Antibody (HY315014) is a rabbit polyclonal antibody detecting AR in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Crocuta crocuta.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human AR (Leu660-Thr919).

Objetivo

Dihydrotestosterone receptor, NR3C4, DHTR, Androgen receptor, AR, Nuclear receptor subfamily 3 group C member 4

Purificación

Purified by antigen affinity column.

Número de acceso

P10275

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Androgen receptor (AR) is a ~99 kDa protein. Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

1. Yang, J. et al. (2009) Endocrine-related cancer 16, 139-53. PMID: 19022849

2. Cui, J. et al. (2011) Cellular and molecular life sciences : CMLS 68, 1091-103. PMID: 20812024

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-AR Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo