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| カタログ番号 | HB586014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ARHGEF15 Polyclonal Antibody (HB586014) is a rabbit polyclonal antibody detecting Rho guanine nucleotide exchange factor 15; Ephexin-5; E5; Vsm-RhoGEF; ARHGEF15; KIAA0915 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human ARHGEF15 (Arg619-Thr741). | ||||||||
| ターゲット | Rho guanine nucleotide exchange factor 15; Ephexin-5; E5; Vsm-RhoGEF; ARHGEF15; KIAA0915 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O94989, Q5FWH6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Rho guanine nucleotide exchange factor 15 (ARHGEF15) is a ~91 kDa protein. Guanine nucleotide exchange factor (GEF) that activates RhoA, playing a role in the regulation of actin cytoskeleton organization. Is involved in the regulation of vascular smooth muscle contractility. Additionally, it negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2. Does not activate RAC1 or CDC42. 1. Ding, X. et al. (2023) Acta neuropathologica 145, 681-705. PMID: 36929019 2. Ogita, H. et al. (2003) Circulation research 93, 23-31. PMID: 12775584 | ||||||||
| 注意事項 | For research use only |
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