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Anti-ARL6 Polyclonal Antibody (HA916014)

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Vista general
Número de catálogoHA916014
Descripción
Anti-ARL6 Polyclonal Antibody (HA916014) is a rabbit polyclonal antibody detecting ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Zebrafish.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human ARL6 (Met1-Thr186).
Objetivo ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q9H0F7, O88848, Q0IIM2, Q5M9P8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

ADP-ribosylation factor-like protein 6 (ARL6) is a ~21 kDa protein. Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade.

1. Jin, H. et al. (2010) Cell 141, 1208-19. PMID: 20603001
2. Seo, S. et al. (2011) PLoS genetics 7, e1002358. PMID: 22072986
3. Wiens, CJ. et al. (2010) The Journal of biological chemistry 285, 16218-30. PMID: 20207729
Nota For research use only
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-ARL6 Polyclonal Antibody

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