

| Каталожный номер | HA916014 | ||||||||
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| Описание |
Anti-ARL6 Polyclonal Antibody (HA916014) is a rabbit polyclonal antibody detecting ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Zebrafish.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human ARL6 (Met1-Thr186). | ||||||||
| Цель | ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9H0F7, O88848, Q0IIM2, Q5M9P8 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | ADP-ribosylation factor-like protein 6 (ARL6) is a ~21 kDa protein. Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. 1. Jin, H. et al. (2010) Cell 141, 1208-19. PMID: 20603001 2. Seo, S. et al. (2011) PLoS genetics 7, e1002358. PMID: 22072986 3. Wiens, CJ. et al. (2010) The Journal of biological chemistry 285, 16218-30. PMID: 20207729 | ||||||||
| Примечание | For research use only |
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