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Anti-ASFV D117L Polyclonal Antibody (VK023014)

Anti-ASFV D117L Polyclonal Antibody
Anti-ASFV D117L Polyclonal Antibody
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  • 100ug
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Vista general
Número de catálogoVK023014
Descripción
Anti-ASFV D117L Polyclonal Antibody (VK023014) is a rabbit polyclonal antibody detecting ASFV D117L in ELISA, IHC, WB.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesAfrican swine fever virus (ASFV)
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant ASFV D117L (Asp2-Thr38&Tyr60-Ser117).
Objetivo Minor capsid protein p17
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q89424
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
WB 1:500-1:2000
IHC 1:50-1:500
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Minor capsid protein p17 is a ~13 kDa protein. Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane. Required for the assembly of the capsid and icosahedral morphogenesis. Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE.

1. Wang, N. et al. (2019) Science (New York, N.Y.) 366, 640-644. PMID: 31624094
2. Suárez, C. et al. (2010) Journal of virology 84, 7484-99. PMID: 20504920
3. Zheng, W. et al. (2022) Frontiers in immunology 13, 941579. PMID: 35844609
Nota For research use only
Imágenes
  • Anti-ASFV D117L Polyclonal Antibody

    Western blot

    Lane 1: recombinant ASFV D117L (Catalog No: VK023012)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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