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| カタログ番号 | VK023014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ASFV D117L Polyclonal Antibody (VK023014) is a rabbit polyclonal antibody detecting ASFV D117L in ELISA, IHC, WB.
Highlights
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| 種反応性 | African swine fever virus (ASFV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant ASFV D117L (Asp2-Thr38&Tyr60-Ser117). | ||||||||
| ターゲット | Minor capsid protein p17 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q89424 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Minor capsid protein p17 is a ~13 kDa protein. Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane. Required for the assembly of the capsid and icosahedral morphogenesis. Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE. 1. Wang, N. et al. (2019) Science (New York, N.Y.) 366, 640-644. PMID: 31624094 2. Suárez, C. et al. (2010) Journal of virology 84, 7484-99. PMID: 20504920 3. Zheng, W. et al. (2022) Frontiers in immunology 13, 941579. PMID: 35844609 | ||||||||
| 注意事項 | For research use only |
Lane 1: recombinant ASFV D117L (Catalog No: VK023012)
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中国武漢市深敦寺路666号C棟、武漢、430206
