中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | VK776014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ASFV pM1249L Polyclonal Antibody (VK776014) is a rabbit polyclonal antibody detecting pM1249L in ELISA, IHC, WB.
Highlights
|
||||||||
| 種反応性 | African swine fever virus (ASFV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant ASFV pM1249L (Gln346-Pro452). | ||||||||
| ターゲット | Minor capsid protein M1249L, pM1249L, Ba71V-060, M1249L | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q65152 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Minor capsid protein M1249L (pM1249L) is a ~144 kDa protein. Together with the penton and the other minor capsid proteins (p17, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. In addition, blocks IFN-beta transactivation mediated by the cGAS-STING pathway and regulates the transcriptional activity of IFN-beta. Mechanistically, suppresses the phosphorylation of host key adapter protein TBK1 and degrades host IRF3 in the cytoplasm. 1. Wang, N. et al. (2019) Science (New York, N.Y.) 366, 640-644. PMID: 31624094 2. Cui, S. et al. (2022) Virus research 319, 198872. PMID: 35853521 | ||||||||
| 注意事項 | For research use only. |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
