Anti-ASFV S273R Polyclonal Antibody (VK573014)

Name: Anti-ASFV S273R Polyclonal Antibody
Brand: abinScience
SKU: VK573014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK573014

Descripción

Anti-ASFV S273R Polyclonal Antibody (VK573014) is a rabbit polyclonal antibody detecting S273R in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

African swine fever virus (ASFV)

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant ASFV S273R (Met1-Ala273).

Objetivo

Cysteine protease S273R, pS273R, 3.4.22.-, Ba71V-111, S273R

Purificación

Purified by antigen affinity column.

Número de acceso

Q00946

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Cysteine protease S273R is a ~31 kDa protein. Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response. Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins. Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD. In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity. Also impairs host FOXJ1-mediated antiviral effect via degradation of FOXJ1.

1. Andrés, G. et al. (2002) Journal of virology 76, 12473-82. PMID: 12438573

2. Zhao, G. et al. (2022) The Journal of biological chemistry 298, 101480. PMID: 34890644

3. Luo, J. et al. (2022) Virulence 13, 740-756. PMID: 35437104

4. Ma, C. et al. (2022) Virologica Sinica 37, 445-454. PMID: 35513267

5. Li, T. et al. (2023) The Journal of biological chemistry 299, 104844. PMID: 37209818

6. Li, YH. et al. (2023) Journal of virology 97, e0194222. PMID: 36856422

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-ASFV S273R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo