Anti-ASFV S273R Polyclonal Antibody (VK573014)

Name: Anti-ASFV S273R Polyclonal Antibody
Brand: abinScience
SKU: VK573014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

VK573014

Описание

Anti-ASFV S273R Polyclonal Antibody (VK573014) is a rabbit polyclonal antibody detecting S273R in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

African swine fever virus (ASFV)

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant ASFV S273R (Met1-Ala273).

Цель

Cysteine protease S273R, pS273R, 3.4.22.-, Ba71V-111, S273R

Очистка

Purified by antigen affinity column.

Номер доступа

Q00946

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Cysteine protease S273R is a ~31 kDa protein. Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response. Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins. Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD. In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity. Also impairs host FOXJ1-mediated antiviral effect via degradation of FOXJ1.

1. Andrés, G. et al. (2002) Journal of virology 76, 12473-82. PMID: 12438573

2. Zhao, G. et al. (2022) The Journal of biological chemistry 298, 101480. PMID: 34890644

3. Luo, J. et al. (2022) Virulence 13, 740-756. PMID: 35437104

4. Ma, C. et al. (2022) Virologica Sinica 37, 445-454. PMID: 35513267

5. Li, T. et al. (2023) The Journal of biological chemistry 299, 104844. PMID: 37209818

6. Li, YH. et al. (2023) Journal of virology 97, e0194222. PMID: 36856422

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-ASFV S273R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа