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| カタログ番号 | HB163024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ATF6 Polyclonal Antibody (HB163024) is a rabbit polyclonal antibody detecting ATF6 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ATF6 (Ala547-Ser632). | ||||||||
| ターゲット | ATF6-alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha, ATF6, Activating transcription factor 6 alpha | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P18850 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) is a ~74 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR). 1. Haze, K. et al. (1999) Molecular biology of the cell 10, 3787-99. PMID: 10564271 2. Yoshida, H. et al. (2001) Molecular and cellular biology 21, 1239-48. PMID: 11158310 3. Yoshida, H. et al. (2001) Cell 107, 881-91. PMID: 11779464 | ||||||||
| 注意事項 | For research use only. |
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