Anti-ATF7IP Polyclonal Antibody (HB362014)

Name: Anti-ATF7IP Polyclonal Antibody
Brand: abinScience
SKU: HB362014
Price: 168 USD
Availability: InStock

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Спецификация:

50ug
100ug

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Каталожный номер

HB362014

Описание

Anti-ATF7IP Polyclonal Antibody (HB362014) is a rabbit polyclonal antibody detecting Activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621; ATF7IP; MCAF; MCAF1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human ATF7IP (Gln1149-Ser1270).

Цель

Activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621; ATF7IP; MCAF; MCAF1

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q6VMQ6, Q7TT18, Q5ZIE8

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Activating transcription factor 7-interacting protein 1 (ATF7IP) is a ~136 kDa protein. Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-mediated heterochromatin formation and gene silencing. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Stabilizes SETDB1, is required to stimulate histone methyltransferase activity of SETDB1 and facilitates the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3).

1. Timms, RT. et al. (2016) Cell reports 17, 653-659. PMID: 27732843

2. Fujita, N. et al. (2003) Molecular and cellular biology 23, 2834-43. PMID: 12665582

3. Wang, H. et al. (2003) Molecular cell 12, 475-87. PMID: 14536086

4. Liu, L. et al. (2009) The Journal of biological chemistry 284, 5165-74. PMID: 19106100

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-ATF7IP Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-ATF7IP Polyclonal Antibody (HB362014)

Обзор

Изображения

Ссылки

Даташит

SDS