

| Numéro de catalogue | HY455014 | ||||||||
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| Description |
Anti-ATP1A1 Polyclonal Antibody (HY455014) is a rabbit polyclonal antibody detecting ATP1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Anguilla anguilla.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ATP1A1 (Thr347-Asp680). | ||||||||
| Cible | Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1, ATP1A1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P05023 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) is a ~112 kDa protein. This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis. 1. Lassuthova, P. et al. (2018) American journal of human genetics 102, 505-514. PMID: 29499166 2. Schlingmann, KP. et al. (2018) American journal of human genetics 103, 808-816. PMID: 30388404 | ||||||||
| Note | For research use only. |
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