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| カタログ番号 | HY455014 | ||||||||
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| 説明 |
Anti-ATP1A1 Polyclonal Antibody (HY455014) is a rabbit polyclonal antibody detecting ATP1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Anguilla anguilla.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ATP1A1 (Thr347-Asp680). | ||||||||
| ターゲット | Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1, ATP1A1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P05023 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) is a ~112 kDa protein. This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis. 1. Lassuthova, P. et al. (2018) American journal of human genetics 102, 505-514. PMID: 29499166 2. Schlingmann, KP. et al. (2018) American journal of human genetics 103, 808-816. PMID: 30388404 | ||||||||
| 注意事項 | For research use only. |
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