

| Numéro de catalogue | HV718014 | ||||||||
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| Description |
Anti-ATXN10 Polyclonal Antibody (HV718014) is a rabbit polyclonal antibody detecting ATXN10 in ELISA, IHC, WB. Suitable for Human, Bovine, Macaca fascicularis, and Pongo abelii.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ATXN10 (Leu116-Ala302). | ||||||||
| Cible | ATXN10, SCA10, Brain protein E46 homolog, Ataxin-10, Spinocerebellar ataxia type 10 protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UBB4 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Ataxin-10 (ATXN10) is a ~53 kDa protein. May play a role in the regulation of cytokinesis. May play a role in signaling by stimulating protein glycosylation. Induces neuritogenesis by activating the Ras-MAP kinase pathway and is necessary for the survival of cerebellar neurons. Does not appear to play a major role in ciliogenesis. 1. Li, J. et al. (2011) Cell cycle (Georgetown, Tex.) 10, 2946-58. PMID: 21857149 2. Tian, J. et al. (2015) Scientific reports 5, 8360. PMID: 25666058 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ATXN10 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: 293T cell lysate
Lane 3: HepG2 cell lysate
Lane 4: Jurkat cell lysate
Lane 5: SKOV3 cell lysate
Lane 6: HL-60 cell lysate
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