Anti-AZIN2 Polyclonal Antibody (HV753014)

Name: Anti-AZIN2 Polyclonal Antibody
Brand: abinScience
SKU: HV753014
Price: 168 USD
Availability: InStock

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100ug

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV753014

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human AZIN2 (Met1-Glu348).

Cible

ODC-p, AZIN2, Antizyme inhibitor 2, KIAA1945, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODCP, AzI2, Arginine decarboxylase

Purification

Purified by antigen affinity column.

Numéro d'accès

Q96A70

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Antizyme inhibitor 2 (AZIN2) is a ~49 kDa protein. Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production. Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking.

1. Kanerva, K. et al. (2008) The Biochemical journal 409, 187-92. PMID: 17900240

2. Kanerva, K. et al. (2010) Experimental cell research 316, 1896-906. PMID: 20188728

Note

For research use only.

Images

Reférences

Fiche technique

Anti-AZIN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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