

| Numéro de catalogue | JN898033 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Bacillus anthracis | ||||
| Applications | ELISA, Neutralization | ||||
| Espèce hôte | Human | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| ID de clone | SAA1377 | ||||
| Cible | Protective antigen, PA, Anthrax toxins translocating protein, PA-83, PA83, Protective antigen PA-20, PA-20, PA20, Protective antigen PA-63, PA-63, PA63, pagA, pag, pXO1-110, BXA0164, GBAA_pXO1_0164 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P13423 | ||||
| RRID | Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1377) (abinScience Cat# JN898033, RRID:AB_3726895) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Protective antigen (PA/pagA) is a ~85 kDa protein. Protective antigen constitutes one of the three proteins composing the anthrax toxin; it mediates attachment to host cells and translocation of edema factor (EF) and lethal factor (LF) into the host cytoplasm. PA associated with LF forms the lethal toxin (LeTx) and causes death when injected; PA associated with EF forms the edema toxin (EdTx) and produces edema. PA induces immunity to infection with anthrax. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Bradley, KA. et al. (2001) Nature 414, 225-9. PMID: 11700562 _x005F_x005F_x000D_
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2. Bradley, KA. et al. (2003) The Journal of biological chemistry 278, 49342-7. PMID: 14507921 _x005F_x005F_x000D_
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3. Santelli, E. et al. (2004) Nature 430, 905-8. PMID: 15243628 _x005F_x005F_x000D_
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4. Lacy, DB. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 13147-51. PMID: 15326297 _x005F_x005F_x000D_
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5. Singh, Y. et al. (1991) The Journal of biological chemistry 266, 15493-7. PMID: 1651334 _x005F_x005F_x000D_
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6. Mock, M. et al. (2001) Annual review of microbiology 55, 647-71. PMID: 11544370 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1377).




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