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| カタログ番号 | JN898033 | ||||
|---|---|---|---|---|---|
| 種反応性 | Bacillus anthracis | ||||
| アプリケーション | ELISA, Neutralization | ||||
| 宿主種 | Human | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1, kappa | ||||
| クローンID | SAA1377 | ||||
| ターゲット | Protective antigen, PA, Anthrax toxins translocating protein, PA-83, PA83, Protective antigen PA-20, PA-20, PA20, Protective antigen PA-63, PA-63, PA63, pagA, pag, pXO1-110, BXA0164, GBAA_pXO1_0164 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P13423 | ||||
| RRID | Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1377) (abinScience Cat# JN898033, RRID:AB_3726895) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Protective antigen (PA/pagA) is a ~85 kDa protein. Protective antigen constitutes one of the three proteins composing the anthrax toxin; it mediates attachment to host cells and translocation of edema factor (EF) and lethal factor (LF) into the host cytoplasm. PA associated with LF forms the lethal toxin (LeTx) and causes death when injected; PA associated with EF forms the edema toxin (EdTx) and produces edema. PA induces immunity to infection with anthrax. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Bradley, KA. et al. (2001) Nature 414, 225-9. PMID: 11700562 _x005F_x005F_x000D_
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2. Bradley, KA. et al. (2003) The Journal of biological chemistry 278, 49342-7. PMID: 14507921 _x005F_x005F_x000D_
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3. Santelli, E. et al. (2004) Nature 430, 905-8. PMID: 15243628 _x005F_x005F_x000D_
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4. Lacy, DB. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 13147-51. PMID: 15326297 _x005F_x005F_x000D_
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5. Singh, Y. et al. (1991) The Journal of biological chemistry 266, 15493-7. PMID: 1651334 _x005F_x005F_x000D_
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6. Mock, M. et al. (2001) Annual review of microbiology 55, 647-71. PMID: 11544370 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1377).
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