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| カタログ番号 | JN922014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Bacillus cereus gajA Polyclonal Antibody (JN922014) is a rabbit polyclonal antibody detecting gajA in ELISA, IHC, WB. Suitable for Bacillus cereus.
Highlights
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| 種反応性 | Bacillus cereus | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Bacillus cereus gajA (Gly258-Gly578). | ||||||||
| ターゲット | Endonuclease GajA, 3.1.-.-, Gabija protein GajA, Nicking endonuclease GajA, gajA, IIE_04982 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | J8H9C1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Endonuclease GajA is a ~66 kDa protein. Component of antiviral defense system Gabija type I, composed of GajA and GajB. Endonuclease that nicks double-stranded DNA within the sequence 5'-TNNNCGGGNNA-3' in the absence of nucleotides (NTP, dNTP and NDPs), cleaving after C-1. Has no detected ATPase activity. Expression of Gabija type I in B.subtilis (strain BEST7003) confers resistance to phages phi105, phi29, rho14, SpBeta and SBSphiC. Expression of Gabija type I in E.coli B (strain ATCC 11303) confers resistance to phage T7. 1. Doron, S. et al. (2018) Science (New York, N.Y.) 359. PMID: 29371424 2. Cheng, R. et al. (2021) Nucleic acids research 49, 5216-5229. PMID: 33885789 3. Antine, SP. et al. (2024) Nature 625, 360-365. PMID: 37992757 | ||||||||
| 注意事項 | For research use only. |
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