Anti-BLOC1S2 Polyclonal Antibody (HB360014)

Name: Anti-BLOC1S2 Polyclonal Antibody
Brand: abinScience
SKU: HB360014
Price: 168 USD
Availability: InStock

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50ug
100ug

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SDS

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Número de catálogo

HB360014

Descripción

Anti-BLOC1S2 Polyclonal Antibody (HB360014) is a rabbit polyclonal antibody detecting Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; Centrosome-associated protein; BLOC1S2; BLOS2; CEAP in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human BLOC1S2 (Glu34-Arg142).

Objetivo

Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; Centrosome-associated protein; BLOC1S2; BLOS2; CEAP

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q6QNY1, Q32WR5, Q9CWG9

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2) is a ~15 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.

1. Starcevic, M. et al. (2004) The Journal of biological chemistry 279, 28393-401. PMID: 15102850

2. Setty, SR. et al. (2007) Molecular biology of the cell 18, 768-80. PMID: 17182842

3. Pu, J. et al. (2015) Developmental cell 33, 176-88. PMID: 25898167

4. Wang, Z. et al. (2004) Journal of molecular biology 343, 71-82. PMID: 15381421

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-BLOC1S2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-BLOC1S2 Polyclonal Antibody (HB360014)

Vista general

Imágenes

Referencias

Datasheet

SDS