Anti-BLOC1S2 Polyclonal Antibody (HB360014)

Name: Anti-BLOC1S2 Polyclonal Antibody
Brand: abinScience
SKU: HB360014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HB360014

Description

Anti-BLOC1S2 Polyclonal Antibody (HB360014) is a rabbit polyclonal antibody detecting Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; Centrosome-associated protein; BLOC1S2; BLOS2; CEAP in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human BLOC1S2 (Glu34-Arg142).

Cible

Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; Centrosome-associated protein; BLOC1S2; BLOS2; CEAP

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q6QNY1, Q32WR5, Q9CWG9

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2) is a ~15 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.

1. Starcevic, M. et al. (2004) The Journal of biological chemistry 279, 28393-401. PMID: 15102850

2. Setty, SR. et al. (2007) Molecular biology of the cell 18, 768-80. PMID: 17182842

3. Pu, J. et al. (2015) Developmental cell 33, 176-88. PMID: 25898167

4. Wang, Z. et al. (2004) Journal of molecular biology 343, 71-82. PMID: 15381421

Note

For research use only

Images

Reférences

Fiche technique

Anti-BLOC1S2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-BLOC1S2 Polyclonal Antibody (HB360014)

Aperçu

Images

Reférences

Fiche technique

SDS