Anti-BLVRB Polyclonal Antibody (HB818014)

Name: Anti-BLVRB Polyclonal Antibody
Brand: abinScience
SKU: HB818014
Price: 168 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD): --

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB818014

Descripción

Anti-BLVRB Polyclonal Antibody (HB818014) is a rabbit polyclonal antibody detecting BLVRB in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human BLVRB (Ala2-Gln206).

Objetivo

FR, Green heme-binding protein, BLVRB, Flavin reductase (NADPH), FLR, NADPH-flavin reductase, GHBP, Biliverdin-IX beta-reductase, NADPH-dependent diaphorase, BVR-B, Biliverdin reductase B

Purificación

Purified by antigen affinity column.

Número de acceso

P30043

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Flavin reductase (NADPH) (BLVRB) is a ~22 kDa protein. Enzyme that can both act as a NAD(P)H-dependent reductase and a S-nitroso-CoA-dependent nitrosyltransferase. Promotes fetal heme degradation during development. Also expressed in adult tissues, where it acts as a regulator of hematopoiesis, intermediary metabolism (glutaminolysis, glycolysis, TCA cycle and pentose phosphate pathway) and insulin signaling. Has a broad specificity oxidoreductase activity by catalyzing the NAD(P)H-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to fetal heme catabolism by catalyzing reduction of biliverdin IXbeta into bilirubin IXbeta in the liver.

1. Cunningham, O. et al. (2000) The Biochemical journal 345 Pt 2, 393-9. PMID: 10620517

2. Smith, LJ. et al. (2008) The Biochemical journal 411, 475-84. PMID: 18241201

3. Wu, S. et al. (2016) Blood 128, 699-709. PMID: 27207795

4. Zhou, HL. et al. (2023) Cell 186, 5812-5825.e21. PMID: 38056462

5. Yamaguchi, T. et al. (1994) The Journal of biological chemistry 269, 24343-8. PMID: 7929092

6. Cunningham, O. et al. (2000) The Journal of biological chemistry 275, 19009-17. PMID: 10858451

7. Li, Z. et al. (2018) The Biochemical journal 475, 1211-1223. PMID: 29500232

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-BLVRB Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-BLVRB Polyclonal Antibody (HB818014)

Vista general

Imágenes

Referencias

Datasheet

SDS