Anti-BLVRB Polyclonal Antibody (HB818014)

Name: Anti-BLVRB Polyclonal Antibody
Brand: abinScience
SKU: HB818014
Price: 168 USD
Availability: InStock

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Каталожный номер

HB818014

Описание

Anti-BLVRB Polyclonal Antibody (HB818014) is a rabbit polyclonal antibody detecting BLVRB in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human BLVRB (Ala2-Gln206).

Цель

FR, Green heme-binding protein, BLVRB, Flavin reductase (NADPH), FLR, NADPH-flavin reductase, GHBP, Biliverdin-IX beta-reductase, NADPH-dependent diaphorase, BVR-B, Biliverdin reductase B

Очистка

Purified by antigen affinity column.

Номер доступа

P30043

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Flavin reductase (NADPH) (BLVRB) is a ~22 kDa protein. Enzyme that can both act as a NAD(P)H-dependent reductase and a S-nitroso-CoA-dependent nitrosyltransferase. Promotes fetal heme degradation during development. Also expressed in adult tissues, where it acts as a regulator of hematopoiesis, intermediary metabolism (glutaminolysis, glycolysis, TCA cycle and pentose phosphate pathway) and insulin signaling. Has a broad specificity oxidoreductase activity by catalyzing the NAD(P)H-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to fetal heme catabolism by catalyzing reduction of biliverdin IXbeta into bilirubin IXbeta in the liver.

1. Cunningham, O. et al. (2000) The Biochemical journal 345 Pt 2, 393-9. PMID: 10620517

2. Smith, LJ. et al. (2008) The Biochemical journal 411, 475-84. PMID: 18241201

3. Wu, S. et al. (2016) Blood 128, 699-709. PMID: 27207795

4. Zhou, HL. et al. (2023) Cell 186, 5812-5825.e21. PMID: 38056462

5. Yamaguchi, T. et al. (1994) The Journal of biological chemistry 269, 24343-8. PMID: 7929092

6. Cunningham, O. et al. (2000) The Journal of biological chemistry 275, 19009-17. PMID: 10858451

7. Li, Z. et al. (2018) The Biochemical journal 475, 1211-1223. PMID: 29500232

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-BLVRB Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-BLVRB Polyclonal Antibody (HB818014)

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