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| カタログ番号 | HS717014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-C2CD3 Polyclonal Antibody (HS717014) is a rabbit polyclonal antibody detecting C2CD3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human C2CD3 (Asn1432-Leu1647). | ||||||||
| ターゲット | C2 domain-containing protein 3, C2CD3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q4AC94 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | C2 domain-containing protein 3 (C2CD3) is a ~260 kDa protein. Component of the centrioles that acts as a positive regulator of centriole elongation. Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. 1. Thauvin-Robinet, C. et al. (2014) Nature genetics 46, 905-11. PMID: 24997988 2. Balestra, FR. et al. (2013) Developmental cell 25, 555-71. PMID: 23769972 | ||||||||
| 注意事項 | For research use only. |
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