

| Número de catálogo | HB707014 | ||||||||
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| Descripción |
Anti-CANX Polyclonal Antibody (HB707014) is a rabbit polyclonal antibody detecting CANX in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Pongo abelii.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CANX (His21-Pro481). | ||||||||
| Objetivo | Major histocompatibility complex class I antigen-binding protein p88, IP90, CANX, p90, Calnexin | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P27824 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Calnexin (CANX) is a ~67 kDa protein. Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-CALNEXIN polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: K562 cell lysate
Lane 3: MCF-7 cell lysate
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