Anti-Capsid Polyclonal Antibody (VK719014) is a rabbit polyclonal antibody detecting Capsid protein C in ELISA, IHC, WB. Suitable for Dengue virus type 1 and Dengue virus type 3.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
Reactivité des espèces
Dengue virus 1 (DENV-1)
Applications
ELISA, IHC, WB
Espèce hôte
Rabbit
Clonalité
Polyclonal
Isotype
IgG
Immunogène
E. coli - derived recombinant Capsid (Asn21-Arg100).
Cible
Genome polyprotein, Capsid protein C, Capsid protein, Core protein, Protein prM, Precursor membrane protein, Peptide pr, Peptide precursor, Small envelope protein M, Matrix protein, Envelope protein E, Non-structural protein 1, NS1, Non-structural protein 2A, NS2A, Serine protease subunit NS2B, Flavivirin protease NS2B regulatory subunit, Non-structural protein 2B, Serine protease NS3, EC:3.4.21.91, EC:3.6.1.15, EC:3.6.4.13, Flavivirin protease NS3 catalytic subunit, Non-structural protein 3, Non-structural protein 4A, NS4A, Peptide 2k, Non-structural protein 4B, NS4B, RNA-directed RNA polymerase NS5, EC:2.1.1.56, EC:2.1.1.57, EC:2.7.7.48, Non-structural protein 5
Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application
Dilution
ELISA
1:5000-1:20000
IHC
1:50-1:500
WB
1:500-1:2000
Stabilité et stockage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte
Genome polyprotein (Capsid) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.
2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804
3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430
4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008
Note
For research use only
Images
Western blot
Western blot analysis was performed using anti-NENV-1 Capsid polyclonal antibody at 1ug/mL on various samples. Lane 1: recombinant DENV-1 Capsid protein C/Core protein (Catalog No: VK719012)
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