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Anti-CASP2 Polyclonal Antibody (HW804014)

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Vista general
Número de catálogoHW804014
Descripción
Anti-CASP2 Polyclonal Antibody (HW804014) is a rabbit polyclonal antibody detecting CASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CASP2 (Gly334-Thr452).
Objetivo Protease ICH-1, ICH1, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD2, CASP-2, Caspase-2, CASP2, NEDD-2
Purificación Purified by antigen affinity column.
Número de acceso P42575
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Caspase-2 (CASP2) is a ~50 kDa protein. Is a regulator of the cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.

1. Droin, N. et al. (2000) Cancer research 60, 7039-47. PMID: 11156409
2. Tinel, A. et al. (2004) Science (New York, N.Y.) 304, 843-6. PMID: 15073321
3. Wang, L. et al. (1994) Cell 78, 739-50. PMID: 8087842
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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