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Anti-CBY1 Polyclonal Antibody (HV591014)

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Aperçu
Numéro de catalogueHV591014
Description
Anti-CBY1 Polyclonal Antibody (HV591014) is a rabbit polyclonal antibody detecting CBY1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human CBY1 (Lys12-Glu115).
Cible ARPP-binding protein, PGEA1, CBY1, Protein chibby homolog 1, ARB1, CBY, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, C22orf2, Cytosolic leucine-rich protein
Purification Purified by antigen affinity column.
Numéro d'accès Q9Y3M2
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Protein chibby homolog 1 (CBY1) is a ~14 kDa protein. Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

1. Takemaru, K. et al. (2003) Nature 422, 905-9. PMID: 12712206
2. Mofunanya, A. et al. (2009) BMC molecular biology 10, 41. PMID: 19435523
3. Hidaka, S. et al. (2004) The Journal of biological chemistry 279, 35009-16. PMID: 15194699
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-CBY1 Polyclonal Antibody

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