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| カタログ番号 | HV591014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CBY1 Polyclonal Antibody (HV591014) is a rabbit polyclonal antibody detecting CBY1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CBY1 (Lys12-Glu115). | ||||||||
| ターゲット | ARPP-binding protein, PGEA1, CBY1, Protein chibby homolog 1, ARB1, CBY, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, C22orf2, Cytosolic leucine-rich protein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y3M2 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein chibby homolog 1 (CBY1) is a ~14 kDa protein. Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. 1. Takemaru, K. et al. (2003) Nature 422, 905-9. PMID: 12712206 2. Mofunanya, A. et al. (2009) BMC molecular biology 10, 41. PMID: 19435523 3. Hidaka, S. et al. (2004) The Journal of biological chemistry 279, 35009-16. PMID: 15194699 | ||||||||
| 注意事項 | For research use only. |
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