

| Número de catálogo | HV164014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CC2D1A (Pro675-Ser944). | ||||||||
| Objetivo | AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q6P1N0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Coiled-coil and C2 domain-containing protein 1A (CC2D1A) is a ~104 kDa protein. Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. | ||||||||
| Nota | For research use only. |
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