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| カタログ番号 | HV164014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CC2D1A (Pro675-Ser944). | ||||||||
| ターゲット | AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6P1N0 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Coiled-coil and C2 domain-containing protein 1A (CC2D1A) is a ~104 kDa protein. Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. | ||||||||
| 注意事項 | For research use only. |
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